Panama competed at the 2011 World Aquatics Championships in Shanghai, China between July 16 and 31, 2011.
Panama qualified 3 swimmers.[1]
| Athlete | Event | Heats | Semifinals | Final | |||
|---|---|---|---|---|---|---|---|
| Time | Rank | Time | Rank | Time | Rank | ||
| Edgar Crespo | Men's 50m Breaststroke | 28.15 | 21 | Did not advance | |||
| Men's 100m Breaststroke | 1:01.94 | 40 | Did not advance | ||||
| Men's 200m Breaststroke | 2:17.38 | 36 | Did not advance | ||||
| Men's 100m Butterfly | 57.24 | 52 | Did not advance | ||||
| Diego Castillo Granados | Men's 200m Butterfly | 2:00.80 | 31 | Did not advance | |||
| Men's 400m IM | 4:32.39 | 30 | Did not advance | ||||
| Athlete | Event | Heats | Semifinals | Final | |||
|---|---|---|---|---|---|---|---|
| Time | Rank | Time | Rank | Time | Rank | ||
| Zamantha Hoss | Women's 50m Freestyle | 28.19 | 49 | Did not advance | |||
| Women's 100m Freestyle | 1:02.12 | 58 | Did not advance | ||||